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Migraine headache is one of the most debilitating disorders in the world and treatments are insufficient. My laboratory studies the neurocircuitry underlying migraine and post-traumatic headache. Our preclinical laboratory focuses heavily on the sensory abnormalities associated with migraine and post-traumatic headache, including photophobia, spontaneous pain and touch hypersensitivity. Our lab’s research uses functional MRI, optogenetic and DREADD approaches to better understand the circuits contributing to those sensory abnormalities. We recently identified the deep cerebellar nuclei as possible sensory integration centers underlying sensory abnormalities in migraine. We are a VA associated lab and part of the VA Center for the Prevention and Treatment of Visual Loss with a special emphasis on Veteran related problems in headache. Post-traumatic headache is similar to migraine and affects about 50% of Veterans who saw combat in war zones. Our hope is to one day identify brain regions that can be manipulated in humans to treat headache. Our promotion of a multi-disciplinary and collaborative approach to tackle these important questions in headache medicine offers trainees room to grow and become wonderful independent scientists.

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Iowa Neuroscience Institute Events

Neuroscience & Pharmacology Seminar - Tom Reh, PhD promotional image

Neuroscience & Pharmacology Seminar - Tom Reh, PhD

Tuesday, September 30, 2025 10:30am to 11:30am
Medical Education Research Facility
Stimulating retinal regeneration in mammals by reprogramming glia: it’s never too late to change their fateTom Reh, PhDProfessorDepartment of Neurobiology and BiophysicsUniversity of Washington School of Medicine
Psychological and Brain Sciences Colloquium: Ulrich Mayr promotional image

Psychological and Brain Sciences Colloquium: Ulrich Mayr

Friday, October 31, 2025 3:30pm to 5:00pm
Psychological and Brain Sciences Building
The Department of Psychological and Brain Sciences is excited to welcome Dr. Ulrich Mayr for this colloquium event. Ulrich is a Lewis Professor and Department Head of the Psychology Department at the University of Oregon. Dr. Mayr's primary research focus is on the relationship between memory, attention, and cognitive control, both from a general and a developmental/life-span perspective. His research methods include behavioral experiments, eye-tracking, and EEG or fMRI neuroimaging. As a...
Iowa Neuroscience Institute Seminar: Michael Yassa, PhD promotional image

Iowa Neuroscience Institute Seminar: Michael Yassa, PhD

Friday, December 5, 2025 12:00pm to 1:00pm
Carver Biomedical Research Building
Seminar Title TBDMichael Yassa, PhDProfessor, Neurobiology and BehaviorJames L. McGaugh Endowed Chair in the Neurobiology of Learning and MemoryProfessor, Psychiatry and Human BehaviorProfessor, NeurologyDirector, Center for the Neurobiology of Learning and MemoryAssociate Dean of Diversity, Equity and Inclusion, Charlie Dunlop School of Biological SciencesUniversity of California, IrvineIowa Neuroscience Institute seminars feature top neuroscientists from around the country sharing their latest...

Carver College of Medicine Events

Pain Research Program Seminar promotional image

Pain Research Program Seminar

Wednesday, September 24, 2025 9:00am to 10:00am
Pappajohn Biomedical Discovery Building
Reduced glymphatic flow and facial allodynia induced by CGRP and mTBI are treated by an α1-noradrenergic receptor antagonist&Serine Hydrolase inhibitor AKU-005 to enhance endocannabinoids for treatment of migraineAdriana Della Pietra, PhDPostdoctoral ResearcherUniversity of Iowa
ACB Seminar Series - Luke Wiseman  promotional image

ACB Seminar Series - Luke Wiseman

Wednesday, September 24, 2025 9:30am to 10:30am
Bowen Science Building
Dr. R. Luke Wiseman, a Professor of Molecular and Cellular Biology from the Scripps Research Institute, will present a seminar titled "Pharmacological Targeting of Stress Responses for Etiologically Diverse Diseases."
Hardin Open Workshops - Mobile Resources for the Health Sciences (Zoom) promotional image

Hardin Open Workshops - Mobile Resources for the Health Sciences (Zoom)

Wednesday, September 24, 2025 1:00pm to 2:00pm
Virtual
Mobile Resources for the Health Sciences

TriNetX Basic Training

Thursday, September 25, 2025 9:00am to 10:00am
Virtual
This training will provide an in-depth look at TriNetX and show you how to use the tool. We will go through building a study, searching for a specific population, and finally what information you can gather from the specific cohort. We will also discuss next steps on getting data extracted for research. After this training you will have a thorough understanding of how to use TriNetX and what the process is to get data extracted for research studies. Register by clicking the virtual event link...
Neuroscience & Pharmacology Seminar - Tom Reh, PhD promotional image

Neuroscience & Pharmacology Seminar - Tom Reh, PhD

Tuesday, September 30, 2025 10:30am to 11:30am
Medical Education Research Facility
Stimulating retinal regeneration in mammals by reprogramming glia: it’s never too late to change their fateTom Reh, PhDProfessorDepartment of Neurobiology and BiophysicsUniversity of Washington School of Medicine