PAIN Retreat Group Photo

Migraine headache is one of the most debilitating disorders in the world and treatments are insufficient. The Sowers laboratory studies the neurocircuitry underlying migraine and post-traumatic headache. Our preclinical laboratory focuses heavily on the sensory abnormalities associated with migraine and post-traumatic headache, including photophobia, spontaneous pain and touch hypersensitivity. Our lab’s research uses functional MRI, optogenetic and DREADD approaches to better understand the circuits contributing to those sensory abnormalities. We recently identified the deep cerebellar nuclei as possible sensory integration centers underlying sensory abnormalities in migraine. We are a VA associated lab and part of the VA Center for the Prevention and Treatment of Visual Loss with a special emphasis on Veteran related problems in headache. Post-traumatic headache is similar to migraine and affects about 50% of Veterans who saw combat in war zones. Our hope is to one day identify brain regions that can be manipulated in humans to treat headache. Our promotion of a multi-disciplinary and collaborative approach to tackle these important questions in headache medicine offers trainees room to grow and become wonderful independent scientists.

lab people

Dr. Sowers was recently featured in Medicine Iowa, a publication of University of Iowa Healthcare featuring stories of research and education at Roy J. and Lucille A. Carver College of Medicine. View the article here: https://medicineiowa.org/fall-2025/levi-sowers-shedding-light-migraine-and-post-traumatic-headache

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MN tracing

Iowa Neuroscience Institute Events

Neuroscience and Pharmacology Seminar - Rong Grace Zhai, PhD promotional image

Neuroscience and Pharmacology Seminar - Rong Grace Zhai, PhD

Tuesday, November 11, 2025 10:30am to 11:30am
Medical Education Research Facility

Harnessing the Power of Drosophila for Therapeutic Discovery for Genetic Neuropathies

Rong Grace Zhai, PhD
Jack Miller Professor of Neurology
Vice Chair of Research
Department of Neurology
University of Chicago

Iowa Neuroscience Institute Seminar: Michael Yassa, PhD promotional image

Iowa Neuroscience Institute Seminar: Michael Yassa, PhD

Friday, December 5, 2025 12:00pm to 1:00pm
Carver Biomedical Research Building

Seminar Title TBD

Michael Yassa, PhD
Professor, Neurobiology and Behavior
James L. McGaugh Endowed Chair in the Neurobiology of Learning and Memory
Professor, Psychiatry and Human Behavior
Professor, Neurology
Director, Center for the Neurobiology of Learning and Memory
Associate Dean of Diversity, Equity and Inclusion, Charlie Dunlop School of Biological Sciences
University of California, Irvine

Iowa Neuroscience Institute seminars feature top neuroscientists from around the country sharing their latest...

Carver College of Medicine Events

Hardin Open Workshops - EndNote Desktop (Zoom) promotional image

Hardin Open Workshops - EndNote Desktop (Zoom)

Tuesday, November 11, 2025 1:00am to 2:00pm
Virtual

EndNote is a reference management tool that helps you to easily gather together your references in one place, organize them, and then insert them into papers and format them in a style of your choosing. This session will walk you through the basics of using EndNote to collect and format your citations. The class will be hands-on, and there will be time for questions at the end.

PLEASE NOTE

Enrollment in HOW is open to all University of Iowa affiliates and residents of the state of Iowa. Advance...

REDCap Advanced Training

Tuesday, November 11, 2025 10:00am to 11:00am
Virtual

This is the fourth step in the REDCap training series. In this training we will cover advanced features such as:

Importing data from a CSV file Ways to customize your data entry experience with form display logic Making your forms more dynamic and personalized with context aware smart variables Sending automated, conditional email alerts Ensuring data is high quality by executing data quality rules, creating data 'missingness' codes, and opening data queries

Register by clicking the...

Neuroscience and Pharmacology Seminar - Rong Grace Zhai, PhD promotional image

Neuroscience and Pharmacology Seminar - Rong Grace Zhai, PhD

Tuesday, November 11, 2025 10:30am to 11:30am
Medical Education Research Facility

Harnessing the Power of Drosophila for Therapeutic Discovery for Genetic Neuropathies

Rong Grace Zhai, PhD
Jack Miller Professor of Neurology
Vice Chair of Research
Department of Neurology
University of Chicago

Pain Interest Group Workshop - Ezgi Yarasir, PT, PhD and Alex Keyes, PhD promotional image

Pain Interest Group Workshop - Ezgi Yarasir, PT, PhD and Alex Keyes, PhD

Wednesday, November 12, 2025 9:00am to 10:00am
Medical Education Research Facility

Exercise-derived biomarkers
Ezgi Yarasir, PT, PhD
Postdoctoral Scholar in Dr. Kathleen Sluka's Lab

Dynorphinergic neurons in the lateral pons inhibit inflammatory, neuropathic, and post-surgical pain via a descending circuit
Alex Keyes, PhD
Postdoctoral Scholar in Dr. Yuriy Usachev's Lab

REDCap MyCap Training

Wednesday, November 12, 2025 10:00am to 11:00am
Virtual

This is the fifth step in the REDCap training series. In this training, we will discuss using the MyCap mobile app for data collection. We will cover features such as:

Creating participants Creating tasks and schedules Active tasks and their unique data output Direct messages and announcements

This training is a demo and not hands-on. After this training, you will have a basic understanding of the MyCap mobile app for REDCap.

Register by clicking the virtual event link above or by going...